Best NMN Supplements 2023: Top 5 Brands Reviewed

Reviewed by Elizabeth Gonzalez Cueto, MD

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Wonderfeel YoungrTM NMN
Omre NMN + Resveratrol
Double Wood NMN
Product Wonderfeel YoungrTM NMN OMRE NMN+ Resveratrol Double Wood NMN
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5.0 stars
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  • Patented formula by a Harvard MD
  • Strong dose – 900 mg NMN per serving
  • Made in the USA – Stabilized and cGMP certified
  • Made with 98% pure NMN and resveratrol
  • Does not contain artificial flavors or additives
  • 30-day money-back guarantee
  • GMO- and gluten-free
  • Tested by third-party laboratories
  • Regulated by the FDA

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A common element in anti-aging supplements is nicotinamide mononucleotide[1] (NMN). It has won the hearts of young people who wish to remain youthful and adults who want to appear young and healthy.

However, selecting effective and reliable NMN supplements has become difficult due to the ever-increasing number of brands that sell NMN anti-aging supplements.

So how do you pick out the best NMN supplement from other less credible or phony ones? What factors should you consider before purchasing NMN products? These questions and more are discussed in detail in our best NMM supplement review. Let’s dive in!

Top 5 Best NMN Supplements In 2023

We put into account the brand’s reputation, customer reviews, affordability, availability, quality of ingredients, and potency of each of the products below. 

Best NMN Supplements In 2023: Top 5 Reviewed & Compared

Wonderfeel YoungrTM NMN

Wonderfeel YoungrTM NMN contains highly bioavailable NMN, which is guarded by strengthening agents that allow cells to perform optimally.

  • Patented formula by a Harvard MD
  • Strong dose – 900 mg NMN per serving
  • Made in the USA – Stabilized and cGMP certified
  • Highest bioavailability
  • Excellent customer reviews
  • Only one size option

Wonderfeel Youngr NMN aims to optimize the health span of humankind. Additional to 900mg NMN, Youngr has potent antioxidants and sirtuin activators, including Ergo, Hydroxytyrosol, Resveratrol, and vitamin d3, which makes this product the best option on the market.

People see a variety of benefits from higher energy and memory to skin elasticity and better sleep. You can check their website to find excellent customer reviews.

For the best results, take two capsules in the morning with healthy high-fat food, such as yogurt, nuts, or avocado. It helps increase the bioavailability of resveratrol, which is beneficial for slowing down aging.

Wonderfeel has an introductory price for both subscription and one-time. You can subscribe and save $15 and lock the price.

OMRE NMN+ Resveratrol

OMRE NMN+ Resveratrol

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OMRE NMN + Resveratrol is made with high-quality, natural products that do not contain fillers.

  • Made with 98% pure NMN and resveratrol
  • Does not contain artificial flavors or additives
  • 30-day money-back guarantee
  • Worldwide shipping
  • Not cost-effective.

Unlike other supplements, OMRE is made with high-quality ingredients and contains 98% pure NMN and resveratrol.

The recommended NMN dose is 500 mg daily, which equals two capsules per day, and is preferably taken in the morning.

A 60-count bottle of NMN + Resveratrol costs $49.97 for first-time customers and $47.47 for repeat customers and returning subscribers. However, if purchased separately, it will cost $90.

Furthermore, they provide a 15 percent discount to their customers, lowering the price to $38.22 for a 60-count bottle, which is calculated at $0.64 per count.

Double Wood NMN

Double Wood NMN

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Double Wood NMN is free of gluten and GMOs and is related to the FDA.

  • GMO- and gluten-free
  • Tested by third-party laboratories
  • Regulated by the FDA
  • Not widely available
  • Not affordable

It is made with high-quality ingredients, manufactured in the USA, and tested by third-party laboratories for potency and purity. 

The recommended daily NMN dosage is between 250 mg to 1500 mg, although the brand only uses 250 mg to 500 mg for its products.

To achieve a total dose of 250 mg, take a 125 mg capsule in the morning and another in the afternoon, or take a 125 mg capsule in the morning and additional capsules within one to three hours to achieve a higher dose.

A 60-count 125 mg bottle costs $48.95 for a first-time purchase and $43.08 for returning and new subscribers.

Quicksilver NAD+ Platinum

QuickSilver does not contain GMOs; vegans can consume them.

  • GMO-free
  • Suitable for vegans
  • Tested by third-party laboratories
  • Employs liposome technology
  • Excellent customer reviews
  • Products must be refrigerated immediately after purchase
  • There is a no-return policy for bad or unsatisfactory products
  • Not affordable

Third-party laboratories test QuickSilver NMN at intervals for purity and stability.

Because it contains platinum, they employ special liposomal technology that imitates the way that NNM is transported in your body and makes use of that knowledge to deliver the vital elements to the precise locations where they can efficiently be utilized.

Also, it is highly absorbent because of its liquid consistency and is more effective than NMN pills or even pure NMN powder. As a result, it is the best option for people who need results quickly.

In addition, this liposomal NMN contains vitamin B12, which maintains the body’s blood and nerve cells. Furthermore, it contains riboflavin, an active ingredient that slows down the aging process, stops inflammation, and offers antioxidant benefits. 

ProHealth Longevity NMN Pro 300

ProHealth Longevity NMN contains Bioperine, which aids digestion and improves the absorption rate.

  • Highly absorbent
  • Does not contain chemical solvents or artificial additives
  • 30-day money-back guarantee
  • Cannot be purchased on the internet
  • Does not provide results from third-party tests

ProHealth Longevity NMN Pro 300 is tested for purity and safety by third-party laboratories at every stage of production.

It is priced at $4.05 per gram. However, a 60-count 300 mg bottle costs $47.30. Nevertheless, you can get it at a discounted price of $42.57 on Amazon stores. 

Although the company offers several amazing discounts and benefits, they support bulk purchases. Therefore, to save more, you’ll have to buy more which, technically, is not considered saving. 

Additionally, the company offers free shipping for orders above $75. For orders less than 75 dollars, they charge $4.99 for first-class shipping and $12 for FedEx shipping, which only takes about two days to be delivered. 

What Is NMN?

NMN is a molecule that occurs naturally in all life forms. It is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and a key component for increasing NAD+ levels in cells.

  • NAD+[2] is a coenzyme that helps NMN supplements perform better and is involved in several metabolic processes. It naturally declines with age and improves muscle performance, immunity, and weight loss.
  • NAD+ precursors are the elements that other substances are produced from. They go through different chemical processes in the body and transform into NAD+. Importantly, NAD+ precursors are further divided into five parts: tryptophan, NA, NAM, NR, and NMN.

In a nutshell, NMN is an enzyme-produced nucleotide molecule that performs important roles in the body’s metabolism and energy production.

Furthermore, NMN supplements provide anti-aging benefits such as increasing longevity and reducing age-related weight gain. It also increases insulin levels and improves brain and heart health.

How Does NMN Work?

NMN slows down the aging process by restoring proper energy balance to the body’s system.

Health Benefits Of NMN Supplements

If taken appropriately, NMN can do the following: 

  • Improve energy metabolism
  • Increase skin elasticity
  • Improve brain and eye function
  • Delay the aging process
  • Improve muscle function and responsiveness 
  • Prevent heart failure 
  • Improve organ function

Importantly, NMN can also do the following: 

  • Reduce the risk of diabetes and obesity
  • Improve fertility

Potential Side Effects

There have been no reported cases of side effects in humans. 

How To Choose The Best NMN Supplements


To avoid purchasing a fake or ineffective product, you must go through this phase and look for as many materials as possible, such as certificates of analysis (COA, also known as lab reports), that verify the credibility and license of any NMN product that you want to buy.


This is another critical factor to consider because, in the NMN industry, quality does not always equate to price. As a result, you should compare the prices of two to three credible supplements to avoid overpaying for inferior products.


It is also important to consider this factor because you may need to buy more supplements when you run out, which could be a challenge if they are not readily available. 


David Sinclair, a professor of genetics at Harvard Medical School, uses 1000mg NMN every day, and the latest and largest human clinical trial to date demonstrates that 600 and especially 900mg NMN per day being significantly more effective than 300 mg NMN per day.

Which Is Better: NMN Or NR?

Though there are no studies or concrete evidence to prove which is superior, several aging experts, scientists, biotech companies, and even NASA and the US military chose NMN over nicotinamide riboside[3] (NR).

They claim that NMN has far more advantages than NR, such as preventing muscle atrophy and protecting astronauts’ DNA from cosmic radiation (R, R, R).

It is also more stable than NR, which is unstable in the bloodstream and is rapidly degraded into Vitamin B3 (R, R) and broken down into nicotinamide (NAM) before reaching the tissues.

Furthermore, NMN can be taken orally and is absorbed without the risk of side effects. In contrast, you can only take NR sublingually, which means only products like Renue by Science sublingual powder can contain NR in its safest form.

Final Thoughts

While going to a medical facility for regular checkups and treatment is a good way to stay young and healthy, it can be a chore if you have to do it too frequently, even on days when you don’t feel like getting out of your comfort zone. 

On those days, you can use NMN supplements as a healthy alternative to periodic checkups and spending time at the hospital. 

However, NMN supplements cannot replace treatment from medical doctors because they only deal with a few specific health conditions. Therefore, supplementing NMN with periodic checkups is advisable for optimal health.

Frequently Asked Questions (FAQs)

Does NMN supplementation work?

Many studies on animals, particularly mice, and humans show that NMN supplements can reverse or slow the aging process and improve cognitive health without the risk of side effects.

Are NMN supplements dangerous?

There is no evidence that NMN supplements are harmful to humans. As a result, it can be considered safe for human consumption.

What is the best way to test the efficacy of NMN supplements?

The best way to determine the efficacy of an NMN product is to measure your NAD levels. The NMN supplement is effective if it has been increased.

When is the best time to take NMN? 

NMN is best taken in the morning, preferably six hours after you wake up.

+ 3 sources

MIDSS adheres to strict procurement guidelines and relies on peer-reviewed studies, academic research institutes, and medical associations. We work mainly with peer-reviewed studies to ensure the accuracy of the information. We avoid the use of tertiary references. You can read about how we ensure the accuracy and timeliness of our content in our editorial process.

  1. (2023). What is NMN? [online] Available at:
  2. Tan, A. and Doig, C.L. (2021). NAD+ Degrading Enzymes, Evidence for Roles During Infection. Frontiers in Molecular Biosciences, [online] 8. doi:10.3389/fmolb.2021.697359.
  3. Mehmel, M., Jovanović, N. and Spitz, U. (2020). Nicotinamide Riboside—The Current State of Research and Therapeutic Uses. Nutrients, [online] 12(6), p.1616. doi:10.3390/nu12061616.


Christine VanDoren, Nutritionist
Personal Trainer, Nutritionist, Health & Wellness Writer
Christine VanDoren created Edge of Longevity, an online personal training company, which helps people all over the world engage in a healthier lifestyle. After becoming an NSCA certified personal trainer and ACE nutritionist, she started spending her time training in the gym and online and creating content for Edge of Longevity, all of which is about how she has worked to better herself, and in turn, hopes to help others better themselves too. She believes the healthier one is, the happier one can be, and through Edge of Longevity, she hopes to spread that happiness to people in every country, every lifestyle, of every age and gender, and ethnicity. She warmly welcomes you to this community of people trying to make a change. In addition to sharing knowledge through her personal training and nutrition services, she enjoys writing articles and blog content over any health and wellness-related topic!


Elizabeth Gonzalez Cueto, MD
Medical Doctor & Medical Writer
My name is Elizabeth and I am a Medical Doctor (MBBS) with experience as a medical and research article writer, reviewer and proofreader. I have worked for the American Journal of Case Reports, the Medical Science Monitor, and Pacific Medical Training as a medical article reviewer and writer. Besides, I have worked as a medical interpreter and translator for Angel City research and SC3 Research group as a medical research assistant for several clinical trials. My academic background includes many international scientific environments like Oxford University, United Kingdom. Hannover Medical School, the University of Tours, France. the Autonomous University of Barcelona and the National Polytechnic Institute in Mexico.