Omega XL Reviews 2022: Ingredients, Side Effects, Pros & Cons

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Reviewed by Sutton, D., MD

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Omega XL
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  • Powerful joint health supplement
  • Improves joint flexibility
  • Supports muscle recovery
  • Natural ingredients, eco-friendly, and drug-free
  • Natural supplement promotes joint health
  • Alleviate joint pain
  • Improves the cholesterol levels
  • Improves heart health
  • Strengthens the immune system
  • Promotes optimal gut health

About The Brand

Dietary supplements restore the nutrient levels in the body and improve the overall health of an individual. Long-chain fatty acids, omega polyunsaturated fatty acids [1], are beneficial for optimizing neuromuscular mechanisms, improving immune profile, regulating blood lipid levels, and enhancing cognitive mechanisms.

Intake of omega-3 in diet and in the form of dietary supplements maintains the ratio between omega-3 and omega-6 fatty acids, which in turn mediates the expression of cytokines, anti-inflammatory, and pro-inflammatory lipid mediators. Intake of omega-3 also resolves metabolic dysfunction, which may have originated from the shift in the ratio of omega-3 and omega-6 fatty acids in the phospholipid cell membrane.

Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are the two common forms of omega-3 fatty acids. These compounds serve as substrates for the synthesis of anti-inflammatory mediators as well as maresins, resolvins, and protectins, which resolve inflammation. These also inhibit the transcription of genes associated with pro-inflammatory mediators. Intake of omega-3 fatty acids also promotes anabolism in the skeletal muscles.

Omega-3 fatty acids

By reducing inflammation, omega-3 fatty acids lower the risk of different chronic health conditions including arthritis [2] pain (osteoarthritis and rheumatoid arthritis). These fatty acids have a positive influence on the maintenance of the health of muscle, by increasing protein synthesis in muscles, improving post-damage recovery, and alleviating muscle soreness.

Omega-3 fatty acids also play an integral role in joint pain relief and osteoarthritis. The local biomechanical factors including abnormal joint loading, frequent joint injuries, and increased magnitude of joint loading contribute to the development of osteoarthritis-related joint pain. In addition to elderly individuals, athletes are at a greater risk of developing joint pain, particularly associated with early osteoarthritis.

New Zealand green-lipped mussel, also known as Perna canaliculus, is a potential source of omega-3 fatty acids. It is known to reduce inflammation, with a significant improvement in the quality of life and reduction in clinical joint symptoms. Perna canaliculus non-polar lipid extract aids in alleviating joint pain, and joint stiffness improves walking pace in osteoarthritis patients and increases grip strength.

Omega XL Reviews

Great HealthWorks is a group of vertically integrated companies, which strives to deliver health and wellness products in the United States. The vertically integrated approach has proved to be a successful strategy. Different products curated by this group of companies include Probiotic XL, Turmeric XL, Vitamin XL-D3, and the famous flagship product, Omega XL.

Omega XL is a potent dietary supplement, which is manufactured using a complex with up to 30 fatty acids beneficial to human health, including omega-3 fatty acids EPA and DHA. The proprietary formula is derived from the New Zealand green-lipped mussels. This unique blend makes Omega XL a distinctive dietary supplement.

This article elaborates on the benefits and effectiveness of Omega XL, developed by Great HealthWorks, on musculoskeletal health and the overall well-being of an individual.

What is Omega XL?

Omega XL is a dietary supplement developed by Great HealthWorks that has numerous health benefits. Among many other dietary supplements developed by the brand Great HealthWorks, Omega XL supports musculoskeletal health, supporting muscle and joint recovery. The product is manufactured using natural ingredients or ingredients derived from nature. The product is eco-sustainable, gluten-free, and non-GMO.

Pros

  • A natural supplement promotes joint health
  • Improves cholesterol levels and helps lose weight
  • Improves cardiovascular health
  • Strengthens the immune system
  • Promotes optimal gut health

Cons

  • Mild to moderate complaints Omega XL users report include nausea, burping, and gastric disturbances.

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Omega XL

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Omega XL

  • Powerful joint health supplement
  • Improves joint flexibility
  • Supports muscle recovery
  • Natural ingredients, eco-friendly, and drug-free

Does It Really Work?

Omega XL comprises ingredients, the health and medical benefits of which are largely supported by research studies. The customers’ reviews on the Omega XL website specify that dietary supplements improve physical activity and joint and muscle strength. The supplements contain lipid extract derived from New Zealand green-lipped mussels and are enriched with omega polyunsaturated fatty acids.

Omega XL Ingredients 

Omega XL is a potent long-term joint health supplement, which strengthens the musculoskeletal system, relieves joint and back pain, and promotes muscle and joint health. The product is made of ingredients including omega-3 fatty acids, free fatty acids, and fat-soluble vitamin E, which are known for alleviating inflammation, by suppressing the synthesis of pro-inflammatory mediators and promoting the production and function of anti-inflammatory mediators.

By alleviating inflammation, the ingredients in the Omega XL dietary supplements relieve joint pain and delayed-onset muscle soreness. In addition to significant relief, these supplements improve the function and health of the immune and cardiovascular systems.

Omega XL Joint Health Supplements for Joint Pain Relief

The Omega XL reviews have mentioned improvement in joint health upon consumption of these dietary supplements. Marine omega-3 sources [3] including New Zealand green-lipped mussels, comprising DHA and EPA, suppress the degradation of the matrix of cartilage at the joints.

The underlying mechanism includes down-regulating and up-regulating the expression of catabolic genes (matrix metalloprotease MMP1, MMP13, and MMP3) and anabolic genes (COL2A1 and AGG) respectively.

In addition to suppressing the degradation of cartilage, the ingredients also suppress the production of pro-inflammatory mediators and enhance the synthesis of anti-inflammatory mediators. The cumulative effect of anti-inflammatory properties is the modulation of the inflammatory response, which ultimately leads to alleviation of pain and discomfort, and improvement in mobility.

Omega XL Review: What Do Real Users Say?

The users appraise the dietary supplements in improving physical activity and movement at the joint. The users report improvement in the overall quality of life and functioning.

“This product is awesome for relieving pain in my shoulders and some arthritic things but the downside is it really creates a really bad breath that’s the only bad thing about it so it’s a either put up with bad breath and no pain or just don’t take it at all the only reason I knew about the bad breath was some little boy at church when I was talking to him said your breath stinks and that’s all.”

Ed Montesano

“I had trouble getting my wedding ring on or off, sometimes I had to wear it for two weeks or not put it on for two weeks due to inflammation. Several weeks after taking 2 pills in the morning and two pills in the evening, inflammation was gone and is still gone. I also noticed that I was hungrier, but lost weight, so I guess it sped up my metabolism, another plus. I continue to take it.”

Yvonne

“A friend of mine recommended these, otherwise I would have never tried them. I’ve tried a lot of these types of supplements with little to no results. I am happy to say that this product does reduce my pain. I have severe arthritis in my shoulder and the Omega XL make it much more tolerable. I will be ordering again.”

Linda Pigg

Alternatives To Omega XL

ProductThorne Research Super EPA & DHA Supplement​Garden of Life Minami Supercritical Platinum Omega 3 Fish OilLongvida Optimized Curcumin Capsules
NameThorne Research Super EPA & DHA Supplement​Garden of Life Minami Supercritical Platinum Omega 3 Fish OilLongvida Optimized Curcumin Capsules
ProsContains omega-3 fish oil
Maintains the normal inflammatory response of the body concerning joints and muscles
Healthy insulin function
Healthy function of the nervous and cardiovascular function
Dual supercritical CO2 extraction technology
Soft gel capsules contain 250% vitamin D and 1100 mg omega-3 fatty acid each
High-concentration omega-3 supplement
No saturated fats as compared to other standard fish oil supplements
The supplements deliver unglucuronidated curcumin throughout the body including the brain
Capable of crossing the blood-brain barrier
Improves brain health
Non-GMO
ConsAdverse reactions in individuals allergic to the ingredients present in the dietary supplementsRelatively expensiveSlightly larger size of the capsule
Not suitable for individuals with soy allergy
Full reviewRead full review Read full review Read full review
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Health Benefits of Omega XL

Omega XL dietary joint pain supplements promote the health and functioning of the muscles and joints, so as to improve mobility and participation in physical activity. The omega-3 fatty acids are essential fatty acids in dietary supplements that also function to improve cardiovascular health, as it improves cholesterol levels and promotes normal blood pressure.

These fatty acids and natural vitamin E also restore the normal function and health of the digestive tract. The dietary supplements strengthen the immune system of the body, facilitating normal responses to pathogen insults. The supplements also restore normal inflammatory responses of the body, thus helping reduce joint pain and muscle soreness.

Omega XL Side Effects

The negative effects of Omega XL dietary supplements are moderate and include abdominal pain, nausea, burping, and gastric disturbances.

How To Take Omega XL?

The company recommends the intake of 4 gel capsules with meals daily. All 4 capsules can be consumed at a single time or can be divided into 2 Omega XL pills during the day and 2 capsules at night.

Omega XL

Omega XL is a potent dietary supplement, which is manufactured using a complex with up to 30 fatty acids beneficial to human health, including omega-3 fatty acids EPA and DHA. The proprietary formula is derived from the New Zealand green-lipped mussels.

  • Natural supplement promotes joint health
  • Improves cholesterol levels and helps lose weight
  • Improves cardiovascular health
  • Strengthens the immune system
  • Promotes optimal gut health
  • Mild to moderate complaints Omega XL users report include nausea, burping, and gastric disturbances.

Omega XL dietary supplements are recommended to be taken in the daily dose of 4 gel capsules, which can be consumed all at once or taken in the form of 2 capsules day and night each. The users are expected to observe improvement in their health after 2 weeks of starting the treatment. However, the best results are expected after 8 weeks of treatment.

The ingredients included in the Omega XL dietary supplement are tocopherol (vitamin E), extra virgin olive oil, and green-lipped mussel oil extract. These ingredients are integral components of the Omega XL proprietary blend. Other ingredients that are part of Omega XL dietary supplements are purified water, gelatin, and glycerin.

The dietary supplement is free of artificial ingredients, yeast, corn, gluten, milk, and shellfish allergen protein. This makes Omega XL safe for individuals who are allergic to shellfish allergen proteins, gluten, and other ingredients. The company provides a 60-day money-back guarantee in case the customers are not satisfied with the dietary supplements or the result.

The dietary supplement users report improved movement at the joints, with greater ease. The users also state that they can engage in physical activities including exercise after the intake of Omega XL dietary supplements.

Does Great HealthWorks Offer Discounts?

The customers can avail of discounts and promotional offers offered by Great HealthWorks, which reduce the Omega XL cost. The buy 1 get 1 free offer along with vitamin XL D3 can be availed on the first order and monthly auto-ship. Great HealthWorks offers up to 30% discount on other products including Heart XL, Trio XL, Vitamin XL, Probiotic XL, and Turmeric XL.

The 60-day money-back guarantee provides users to buy Omega XL supplements and return their purchase and demand a refund in case the users are not satisfied with the purchase. The consumers shall return empty bottles or unused products to the company. This shall be done within 30 days from the order cancellation date.

Final Thought

Omega XL dietary supplements by Great HealthWorks is a powerful joint health supplement that comprises vitamin E, natural monounsaturated olive oil, and omega-3 fatty acids. The medical benefits are supported by clinical research, however, the parent website does not cite research supporting Omega XL claims. The health benefits include improvement in joint, muscle, cardiovascular, and immune system functioning as well as suppression of muscle soreness and treating joint pain. The supplements are allergen free and may be associated with mild to moderate side effects.

Frequently Asked Questions

Can individuals allergic to shellfish consume Omega XL supplements?

Although the extraction removes allergen proteins, individuals allergic to shellfish shall be taking Omega XL joint supplements under the supervision of their healthcare providers.

How long does it take for the dietary supplements to work?

One may observe the results 2 weeks after starting the treatment, however, the results are best observed 8 weeks after the treatment begins.

Does Omega XL dietary supplement contain marine-sourced omega-3 fatty acids?

The dietary supplements contain omega-fatty acids derived from New Zealand green-lipped mussels.

How many capsules of the supplement shall I take?

As per the recommendations, one shall consume 4 gel capsules with meals each day.

How does Omega XL dietary supplement support joint health?

Omega XL works by mediating catabolism and anabolism of muscles and cartilage at the joints. The supplements work by improving physical activity and overall well-being and reducing joint pain. In addition to relieving painful joints, the supplements also alleviate joint discomfort.

What are the side effects of Omega XL supplements?

The moderate side effects of Omega XL include nausea, burping, and digestive disturbances such as diarrhea.

+ 7 sources

MIDSS has strict procurement guidelines and relies on peer-reviewed studies, academic research institutes and medical associations. We work primarily with peer-reviewed studies to ensure accuracy. We avoid using tertiary references. For more information on how we ensure the accuracy and timeliness of our content, please see our editorial policy.

  1. McGlory, C., Calder, P.C. and Nunes, E.A. (2019). The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease. Frontiers in Nutrition, [online] 6. doi:10.3389/fnut.2019.00144.
  2. Gammone, M., Riccioni, G., Parrinello, G. and D’Orazio, N. (2018). Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport. Nutrients, [online] 11(1), p.46. doi:10.3390/nu11010046.
  3. Buddhachat, K., Siengdee, P., Chomdej, S., Soontornvipart, K. and Nganvongpanit, K. (2017). Effects of different omega-3 sources, fish oil, krill oil, and green-lipped mussel against cytokine-mediated canine cartilage degradation. In Vitro Cellular & Developmental Biology – Animal, [online] 53(5), pp.448–457. doi:10.1007/s11626-016-0125-y.
  4. Omega-3 fatty acids: Medlineplus drug information [Internet]. MedlinePlus. U.S. National Library of Medicine; [cited 2022Jul23]. Available from: https://medlineplus.gov/druginfo/meds/a607065.html
  5. McGlory, C., Calder, P. C., & Nunes, E. A. (2019). The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease. Frontiers in nutrition, 6, 144. https://doi.org/10.3389/fnut.2019.00144
  6. Gammone, M. A., Riccioni, G., Parrinello, G., & D’Orazio, N. (2018). Omega-3 Polyunsaturated Fatty Acids: Benefits and Endpoints in Sport. Nutrients, 11(1), 46. https://doi.org/10.3390/nu11010046
  7. Buddhachat, K., Siengdee, P., Chomdej, S., Soontornvipart, K., & Nganvongpanit, K. (2017). Effects of different omega-3 sources, fish oil, krill oil, and green-lipped mussel against cytokine-mediated canine cartilage degradation. In vitro cellular & developmental biology. Animal, 53(5), 448–457. https://doi.org/10.1007/s11626-016-0125-y

ABOUT THE AUTHOR

Bayer, R., MD
Medical Writer & Medical Doctor
Rick is a Final Year Medical Student. Passionate about medicine, fitness and personal growth, he is always ready to challenge himself to accomplish tasks and especially spread correct medical information to people. Rick is a long-term medical writer for several sites. With more than 5 years of experience in medical writing, he has completed 200+ projects with private and business clients.

ABOUT MEDICAL REVIEWER

Sutton, D., MD
Medical Writer & Editor
Drew is a retired ENT doctor who now lives in the Southeastern US. He was a member of the American Academy of Otolaryngology and a Fellow of the American College of Surgeons. He has a bachelor’s degree in Biology and Psychology and an MD degree. He completed his internship in General Surgery and Residency in Otolaryngology-Head and Neck Surgery and practiced for almost 30 years in all aspects of ENT, including a specialization in disorders of the ear and skull base. Drew is passionate about communicating his clinical experiences and making his knowledge more accessible to the general public by medical writing.