Best Muscle Building Supplements 2023: Top 7 Options To Gain Muscle

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Reviewed by Drew Sutton, MD

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Testo Prime
CrazyBulk Testo-Max
D-Bal Max
Product TestoPrime CrazyBulk Testo-Max D-Bal Max
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Pros
  • Best for testosterone
  • Scientifically backed
  • Best for testosterone
  • Contains micronutrients
  • Best overall
  • Best testimonies
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Sports supplements are used for the purpose of weight loss, muscle gain and exercise performance. 

Supplements like testosterone Boosters with ingredients in fenugreek and ginseng can boost natural testosterone by 20-50%[1]

Supplements like protein powders and pre workouts can also increase muscular protein synthesis and boost acute exercise performance. 

A lot are in a dilemma in deciding which sports supplement to use. For this reason, we have put together an article that covers:

  • “Best Supplements for Weight Loss and Muscle Gains in 2023“
  • “Do They Actually Work?”
  • “7 Best Supplements Discussed”
  • “Types of Bodybuilding Supplements”
  • “Common Ingredients In Muscle Building Supplements”
  • “How To Choose The Best Muscle Building Supplements”

Best Supplements for Muscle Growth In 2023

Do They Actually Work?

These supplements certainly do work but through different mechanisms. Some of these supplements may work by boosting testosterone and growth hormone. Others may work through increasing dietary protein synthetic response. Or through means of ergogenic and exercise performance.

Best Muscle-Building Supplements In 2023: Top 7 Aids Most Recommended

TestoPrime

Overall a good product that surprisingly is actually backed by scientific literature. It may help normalize testosterone levels and benefit health and fitness.

  • May “normalize” testosterone
  • May induce muscle growth and strength
  • May help lose weight via increased energy expenditure 
  • May reduce muscle fatigue
  • Increase libido and sex drive
  • May improve mood and confidence
  • FDA approved
  • Scientifically backed
  • Natural ingredients
  • Convenient to get potent ingredients in one supplement  
  • Low risk of side effects
  • No prescription required
  • One time payment (no subscriptions)
  • 100% money back guarantee
  • Expensive considering the ingredients are available in natural herbs 
  • Pill form may not suit all users

The product is backed by both anecdote and clinical research. Customers have claimed these are great supplements for muscle growth as well as exercise recovery and performance. Not to mention, that real users were able to improve their level of sex drive, libido. Mood and confidence. In terms of side effects, no one has claimed that they experienced any major side effects to my knowledge. 
Moving on to the research[2] that the supplement company has documented. They have claimed that it increased strength by 138.7%, convert 12%* more fat into energy, burn as much as 16%* of body fat, improve endurance by up to  92.2%* and decrease stress by up to 71.6%*.

CrazyBulk Testo-Max

The selling point for me is that this product has some ingredients that can help towards normalizing testosterone, which can then improve lean body mass. Furthermore, CrazyBulk offers a world wide shipping, thereby reaching more customers in need around the globe.

  • Contains micronutrients
  • May help prevent micronutrients deficiency and adverse effects
  • Research backed herbs in their supplement i.e., ginseng and nettle leaf extract
  • Detailed information on the CrazyBulk website for safe effective use of their supplement
  • World wide shipping
  • May help “normalize” testosterone
  • May increase muscle mass and strength
  • May help lose weight via increased energy expenditure
  • May reduce muscle fatigue
  • Increase libido and sex drive
  • May improve mood and confidence
  • Low risk of side effects
  • No prescription required
  • Gelatin capsules are not suitable for vegetarians, vegans, or halal/kosher consumers
  • Odd number of capsules. The recommended daily dose is 4 capsules per day while there are 30 per container, 2 left over capsules on day 8

If you visit the website you can see multiple testimonials and transformation images[3]. I kid you not, with the use of CrazyBulk Testo-Max people have gone from looking really unhealthy with a large amount of body fat to lean and fit with lots of muscle growth. 

Overall the CrazyBulk Testo-Max muscle building pills are highly rated by customers with almost perfect customer reviews. Customers that have used the product have claimed that it is effective for recovery, strength, focus and much more. To top it up, the amount of return customers is very impressive.

D-Bal Max

What I admire most about this product is the inclusion of certain micronutrients like zinc. These micronutrients may prevent deficiency and maintain normal functions like testosterone production. 

  • Variety of micronutrients that are linked to testosterone
  • May boost muscle growth
  • Safer than anabolic steroids
  • Informative website
  • Good amount of testimonials
  • The claims are too far fetched
  • No research to back the supplement up
  • Cherry picked data to support a bias that is not that relevant  

The good thing is, that in the practical setting there is a healthy amount of reviews and testimonials to suggest that D-Bal Max may work. People have claimed that they are “Stronger and more cut” “arms look leaner” “packing on Muscle” “Best workout supp” “Great pumps super strength”.

HyperGH 14X

The product must be admired for its safety and certifications from many different organizations. Whether the product works is another rant altogether. But I must say that there is an element of promise and perhaps even a placebo effect to start exercising more effectively for better results. 

  • No harmful side effects 
  • GMP certified
  • Non GMO
  • Made in USA with good ingredients
  • Free Shipping
  • Claim to increase HGH by 14%
  • Ingredients list has not been displayed on their website
  • No research to back their claims
  • HGH is not really that well linked to muscle mass 

I would not say that HyperGH 14X is particularly a muscle building supplement. The company claims, HyperGH 14X may increase GH by 14%. Although elevating human growth hormone does not really have many muscle growth properties, it may contribute to overall health i.e., skin, bones, hair etc.

CrazyBulk D-BAL

The product has some good quality ingredients overall. The selling point for me would be the inclusion of ashwagandha, which has a strong link with testosterone and mental health.

  • Most potent in testosterone boosting ingredients
  • Supplement for muscle growth
  • Not toxic for organs
  • May boost exercise performance
  • May contribute towards muscular protein synthesis
  • May aid in better mental and physical health
  • The ingredients can easily be obtained from foods and cheaper supplements
  • The price is a little high for what you get

Another muscle growth supplement through the means of boosting testosterone.  Users that have used this have shown some serious modification[4] in physicality with very impressive before and after pictures. Testimonials have been put through that CrazyBulk D-BAL helped users gain muscle, increased strength, stamina, endurance etc.

Tri-Protein

The best supplement to boost protein synthesis of the muscles and induce some muscle growth. We must also highlight that it is low in calories so can easily be included into a healthy diet.

  • Increases muscle protein synthesis
  • Contains all 9 essential amino acids
  • Promotes muscle growth in the long term
  • Highly bioavailable
  • Suppresses appetite
  • Has a high thermic effect (burns a more calories to digest, process and metabolize)
  • Low calories (97 calories) 
  • Transparent supplement with fitness experts using it 
  • Subscription based, some users do not want to keep taking the same supplement
  • Unproven statements
  • Ingredients list does not break down the concentration of each amino acid 

I have actually tried this supplement. Not only were the flavors great, I was able to maintain and promote muscle growth while using it. I am certain that it maximized protein synthesis through its formula with all 9 essential amino acids and 3 branched chain amino acids, specifically leucine. 

To top it off, Tri-protein has included a variety of proteins that “absorb” at different rates so it is perfect to be ingested at any time of the day. Personally, I had it for breakfast, post workout and before bed. 

Certainly amongst the best muscle growth supplements for me!

Intensive Pre-Train

The product can work as a pre workout. It may have a “pump” effect coupled with buffering lactate for great endurance.

  • Increased Vasodilation, followed by blood and oxygen uptake for better exercise performance
  • Enhanced focus
  • Ingredients for better absorption
  • May boost testosterone 
  • May increase muscle mass
  • Increase muscle carnosine 
  • May act as a buffer for lactate for better endurance performance
  • Natural and legal ingredients
  • Athlete approved
  • Subscription based, some users may not want to take the supplement for long periods
  • A vital ingredient called caffeine is missing, this works as an ergogenic aid

Another product that I have tried personally. The boost of energy was not that great, but it did give me that tingly sensation on my skin and great “pumps” in the gym. In fact, I was able to run faster and longer before feeling the lactic acid kick in.

 GREAT SUPPLEMENT! 

Types of Bodybuilding Supplements

Testosterone Boosters

Testosterone Boosters[5] are not my go to. They may have a use case for those who are falling short of the physiological range of testosterone of ~300-950 ng/DL. Variables that may be causing a drop in testosterone are usually age related. 

Testosterone Boosters usually contain some micronutrients and herbs that have shown to stimulate an increase in testosterone. Upon reaching a physiological range of testosterone, an individual may experience an increase in muscle mass.

Protein Supplements

There are many types of protein supplements. I have highlighted some popular products amongst bodybuilders.

  • Whey Protein Powder – Whey protein is the bioavailable form of protein. It contains all essential amino acids[6] and branched chain amino acids. With the highest concentration of branched chain amino acid called Leucine[7] (11%), it can maximize muscle protein synthesis. 
  • Weight gainers – Weight gainers also contain essential amino acids. However these have added carbohydrates and fats, which increase its overall calories. Hence why it may increase weight, by exceeding maintenance levels of calories.
  • Protein bars – More of a solid form of protein. They usually have some complex carbohydrates and fats to make a whole meal. 
  • Branched Chain Amino Acids – The 3 branched chain amino[8] acids include; leucine, isoleucine and valine. These are responsible for triggering muscular protein synthesis thesis. They are found in protein based foods, but also formulated into BCAA powders and pills. To be honest, they do not have the best use case, but may elongate the response of protein foods, when they are ingested 2 hrs afterwards. 

Pre Workout Supplements 

Pre workouts[9] are used as an exercise ignitor. The perfect formula and best ingredients are debatable, but what I generally like to see in pre workouts includes:

  • Caffeine – Caffeine is an ergogenic aid that inhibits the “relaxation receptors” called adenosine. This then activates the central nervous system, which then increases workout output amongst other benefits.
  • Citrulline malate – Citrulline malate is converted into arginine via the kidneys. Arginine can then increase the nitric oxide concentration in the bloodstream. This outcome relaxes the smooth muscles and causes vasodilation. From here we will see an increased uptake of oxygen and blood to the muscle, which can modify exercise performance.
  • Beta-alanine – Beta-alanine increases muscle carnosine. Muscle carnosine is known to buffer lactate. If you engage in endurance exercises you have experienced the burning feeling in the muscles. So basically beta alanine slows this process down.

Pre workout supplements are usually taken 30-45 minutes before exercise. 

Creatine Supplements

Although it is not on our list, creatine is one of the best supplements for muscle building. It is a well known fact that creatine can be used as energy via the creatine phosphate energy system. This system provides quick and powerful energy during short bursts of activity like sprinting and weight lifting. 

Creatine supplements like monohydrate, may saturate the muscle cells with creatine phosphate over time. This means that you will get a bit of extra power based energy.

To take creatine monohydrate[10], one must either supplement with 5g per day (1 tsp) which will saturate the muscles within 28 days. On the other hand, creatine monohydrate can be loaded with around 20-25g per day, which may saturate the muscle cells within 1 week. Once muscle cells are saturated a maintenance dose of 5g per day must be taken. 

Cycling creatine is not required. Creatine has NOT shown to be dangerous, even with long term use.

Common Ingredients In Muscle Building Supplements

In terms of muscle growth supplement, we will see the most effects with whey protein and creatine. Some often see these a lot in muscle building supplements. These ingredients can switch on a muscle building response and improve strength training performance the most. In the long term, these ingredients will promote muscle mass and strength. 

We usually see other ingredients too, like vitamin b12, zinc, and magnesium, fenugreek, ashwagandha etc… These ingredients may have some benefits for hormone levels and overall strength. However, in my opinion are these nowhere near as important as whey and creatine for muscle mass in my opinion. 

How To Choose The Best Muscle Building Supplements

Testosterone Booster

Other ingredients like ashwagandha, fenugreek, tongkat ali, zinc etc. May be effective in boosting testosterone[11]. Although these ingredients are not always necessary, they may be advantageous for someone trying to maintain normal testosterone levels.

Protein Supplement

I would suggest going for a protein supplement that has around 20-40g of protein per serving. The protein must contain all of the 9 essential amino acids. It must be concentrated with a sufficient amount of Leucine ~2-3g per serving[12]. This way you can maximize the muscle building response for ~3 hrs.  

If the goal is to put on lean muscle mass, then  you may want to go for a protein or muscle building supplement that is low in calories. I would not purchase a product with more than 200 calories per serving. 

On the other hand, if you are attempting to put on as much mass as possible then you may want a supplement with more calories. In regards to mass, we are talking about body fat, muscle, glycogen and water. Typically, these types of supplements should contain over 800-900 calories per serving. These calories can help promote a caloric surplus which would increase mass over time.

Pre Workout Supplement

When we are looking to purchase a pre workout the first ingredient I look for is caffeine. Caffeine should be at a dose of 200-300 mg (~3-6 mg/kg)[13]

Scanning through the ingredients list, I always look for a pump product I.e., citrulline malate[14]. A dose of 6000-10000 mg has shown to work best.

Third on my pre workout list is beta alanine[15]. As mentioned, beta alanine is a buffer of lactate. Doses of 3-4g should do the trick. 

How Much Do Muscle Building Supplements Cost?

The price of a supplement really depends on the type and net content.

Testosterone Boosters

For testosterone boosters, we could be looking at over $60 per one month’s worth of capsules.

Protein Supplements

For a protein supplement we are looking at around $50-$70 for a 2.2lb container. 

Pre Workout Supplements

A good quality pre workout could cost you around $60 for 17.637 oz in net weight. 

Final Thoughts

We have highlighted 7 weight loss/muscle building supplements. This includes: 4 testosterone boosters, 1 HGH booster, 1 protein supplement and 1 pre workout. Even though it was not on our list, creatine monohydrate is also a great supplement that you could look into. 

When we are looking to purchase a testosterone booster product, we must look out for a herb like fenugreek that has shown to increase testosterone. 

When it comes to protein powder, it needs all of the essential amino acids and at least 20g of protein per serving. 

Last but not least, pre workouts! Personally, I like to see ingredients like caffeine (200-300mg) citrulline malate (6-10g) beta-alanine (3-4g). 

One more thing to note, supplements are not cheap in my opinion. An average supplement will cost around $60.

Frequently Asked Questions (FAQs)

Best type of supplement for muscle building and weight loss?

Without a doubt a protein powder with all of the needed amino acids is best.

Do testosterone boosters build muscle?

Not Always! Say if you have lost muscle due to low testosterone, testosterone Boosters may help normalize natural testosterone to put some muscle back on.

How do pre workouts help build muscle and lose weight?

They increase energy expenditure naturally and they promote a better exercise performance to build muscle and lose weight.

+ 15 sources

MIDSS adheres to strict procurement guidelines and relies on peer-reviewed studies, academic research institutes, and medical associations. We work mainly with peer-reviewed studies to ensure the accuracy of the information. We avoid the use of tertiary references. You can read about how we ensure the accuracy and timeliness of our content in our editorial process.

  1. Almaiman, A.A. (2018). Effect of testosterone boosters on body functions: Case report. International journal of health sciences, [online] 12(2), pp.86–90. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870326/ [Accessed 14 Apr. 2023].
  2. TestoPrime UK. (2015). Buy Testosterone Online | Natural Testosterone Booster – TestoPrime UK. [online] Available at: https://testoprime.co.uk/#Ingredients [Accessed 14 Apr. 2023].
  3. CrazyBulk UK. (2020). TESTO-MAX. [online] Available at: https://crazybulk.co.uk/products/testo-max [Accessed 14 Apr. 2023].
  4. CrazyBulk UK. (2020). D-BAL. [online] Available at: https://crazybulk.co.uk/products/d-bal [Accessed 14 Apr. 2023].
  5. Almaiman, A.A. (2018). Effect of testosterone boosters on body functions: Case report. International Journal of Health Sciences, [online] 12(2), pp.86–90. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870326/.
  6. Wilson, J.M., Wilson, S.M.C., Loenneke, J.P., Wray, M., Norton, L.E., Campbell, B.I., Lowery, R.P. and Stout, J.R. (2012). Effects of Amino Acids and their Metabolites on Aerobic and Anaerobic Sports. Strength and Conditioning Journal, [online] 34(4), pp.33–48. doi:https://doi.org/10.1519/ssc.0b013e31825663bd.
  7. Wilson, J.M., Wilson, S.M.C., Loenneke, J.P., Wray, M., Norton, L.E., Campbell, B.I., Lowery, R.P. and Stout, J.R. (2012). Effects of Amino Acids and their Metabolites on Aerobic and Anaerobic Sports. Strength and Conditioning Journal, [online] 34(4), pp.33–48. doi:https://doi.org/10.1519/ssc.0b013e31825663bd.
  8. Wilson, J.M., Wilson, S.M.C., Loenneke, J.P., Wray, M., Norton, L.E., Campbell, B.I., Lowery, R.P. and Stout, J.R. (2012). Effects of Amino Acids and their Metabolites on Aerobic and Anaerobic Sports. Strength and Conditioning Journal, [online] 34(4), pp.33–48. doi:https://doi.org/10.1519/ssc.0b013e31825663bd.
  9. Jagim, A., Harty, P. and Camic, C. (2019). Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements. Nutrients, [online] 11(2), p.254. doi:https://doi.org/10.3390/nu11020254.
  10. Hultman, E., Soderlund, K., Timmons, J.A., Cederblad, G. and Greenhaff, P.L. (1996). Muscle creatine loading in men. Journal of Applied Physiology, [online] 81(1), pp.232–237. doi:https://doi.org/10.1152/jappl.1996.81.1.232.
  11. Almaiman, A.A. (2018). Effect of testosterone boosters on body functions: Case report. International journal of health sciences, [online] 12(2), pp.86–90. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870326/ [Accessed 14 Apr. 2023].
  12. Wilson, J.M., Wilson, S.M.C., Loenneke, J.P., Wray, M., Norton, L.E., Campbell, B.I., Lowery, R.P. and Stout, J.R. (2012). Effects of Amino Acids and their Metabolites on Aerobic and Anaerobic Sports. Strength and Conditioning Journal, [online] 34(4), pp.33–48. doi:https://doi.org/10.1519/ssc.0b013e31825663bd.
  13. Jagim, A., Harty, P. and Camic, C. (2019). Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements. Nutrients, [online] 11(2), p.254. doi:https://doi.org/10.3390/nu11020254.
  14. Jagim, A., Harty, P. and Camic, C. (2019). Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements. Nutrients, [online] 11(2), p.254. doi:https://doi.org/10.3390/nu11020254.
  15. Jagim, A., Harty, P. and Camic, C. (2019). Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements. Nutrients, [online] 11(2), p.254. doi:https://doi.org/10.3390/nu11020254.

ABOUT THE AUTHOR

Zaakir Shakoor, Nutritionist
Nutrition, Exercise & Health Specialist/Writer
Zack Shakoor Kayani was born and raised in the South East of England/London. Zack has attained a bolus of knowledge regarding biosciences through academia and his career experiences. In terms of his educational background, he has a Bachelor of Science in Kinesiology (Hons.), a Postgraduate diploma in sports nutrition with the International Olympic Committee, and a Master of Science in Nutritional Sciences from Middlesex University. Zack has been fortunate enough to apply his Exercise Science and Nutrition Knowledge to aid Hundreds if not Thousands of Patients and Athletes, providing 1-1 consultation, Personal training, Information sheets, offering recommendations to collate nutrition and exercise programs, etc. Not to mention, in 2022, he authored a book called 'The 'Good' Coach Weight Loss Solution.

ABOUT MEDICAL REVIEWER

Drew Sutton, MD
Medical Writer & Editor
Drew is a retired ENT doctor who now lives in the Southeastern US. He was a member of the American Academy of Otolaryngology and a Fellow of the American College of Surgeons. He has a bachelor’s degree in Biology and Psychology and an MD degree. He completed his internship in General Surgery and Residency in Otolaryngology-Head and Neck Surgery and practiced for almost 30 years in all aspects of ENT, including a specialization in disorders of the ear and skull base. Drew is passionate about communicating his clinical experiences and making his knowledge more accessible to the general public by medical writing.
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