Best CBD Oil 2023: Top 10 Rated & Buyer’s Guide

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Reviewed by Sutton, D., MD

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CBDfx Oil
CBDistillery
Spruce CBD Oil
Product CBDfx CBDistillery Spruce CBD
Rating ⭐⭐⭐⭐⭐
5.0 stars
⭐⭐⭐⭐
4.0 stars
⭐⭐⭐⭐
4.0 stars
Pros
  • High potency
  • Offers full-, broad spectrum, and CBD isolate options
  • Vegan friendly
  • Convenient and portable 30 mL tincture bottle
  • Free shipping
  • High potency
  • Third-party lab testing
  • No artificial sweeteners or additives
WHERE TO BUY

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The hemp plant is one of the main sources of cannabidiol oil. CBD[1] can also be obtained from marijuana; however, it comes with high THC levels, which have psychoactive properties. CBD oil is then mixed with hemp seed oil, coconut oil, or other carrier oils, and depending on the extraction method, CBD products can be broad-spectrum or full-spectrum. The latter contains all the chemical compounds[2] of a cannabis plant, while the former contains all the cannabinoids except THC. CBD is the purest form of CBD; therefore, it is free from all chemical compounds.

CBD oil is becoming the most popular natural remedy for improving health and wellness. Also, CBD products are becoming prevalently trendy as they offer a vast range of health benefits, from physical to mental relief. CBD oil products can relieve pain, alleviate anxiety, prevent neurological symptoms such as seizures, and so much more. These products include gummies, soft gel capsules, tinctures, bath bombs, and topical CBD oil. CBD products contain different CBD oil spectrum, including full spectrum, broad spectrum, and CBD isolate. People choose these CBD oil products depending on the desired result and the body’s tolerance to CBD. Also, you find these products in multiple flavors and potencies and select whichever is more convenient.

CBD is legalized in most states; however, CBD products are not FDA-regulated. This reason might result in a high rise of mediocre quality products that might harm your health. This article will offer a comprehensive review of some of the best companies in the CBD industry that offer high quality CBD oil products. High-quality CBD products are made from top-tier quality hemp extract. These brands have a vast range of CBD products that come in multiple potencies and flavors. They have undergone third-party testing to guarantee safety, efficacy, purity, and quality.

10 Best CBD Oil Products In The Market 2023

Which CBD Oil Is Best?

Studies[3] show that the consumption of CBD for a variety of health and wellness purposes is prevalently rising.  People consume CBD for pain relief, to improve sleep quality, to relieve anxiety, and many more. With this rising trend of CBD oil, the CBD industry is flooded with numerous companies claiming to have the best CBD oil items. It is acceptable to be overwhelmed and even skeptical about the quality of some of these CBD products. We have taken the time and meticulously analyzed some of the best brands in the market based on various crucial features. Stellar-quality CBD products are made from organic hemp plants and come with a certificate of Analysis guaranteeing that the products are free from molds, heavy metals, or pesticides. They also undergo third-party laboratory testing in ISO 17025-certified laboratories.

These brands use organic hemp extract to make some of the highly reputable and most effective CBD-infused products. We have ranked these CBD companies based on flavor options, dietary friendliness, potencies, and prices. Dietary friendliness implies that we evaluate the carrier oil’s quality and check whether the CBD product is gluten-free; or vegan-friendly. Let us dive right in, shall we?

CBDfx Oil
CBDfx
  • High potency
  • Offers full-, broad spectrum, and CBD isolate options
  • Vegan friendly

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Spruce CBD Oil
Spruce CBD
  • High potency
  • Third-party lab testing

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Joy Organics CBD Oil
Joy Organics
  • THC free
  • Free shipping
  • USDA approved organic

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CBDPure Oil
CBDPure
  • All-organic
  • 90-day money-back guarantee
  • Full spectrum CBD

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NuLeaf Full Spectrum Hemp CBD Oil
Nuleaf Naturals
  • Third-party lab tested
  • Contains 60 mg of CBD
  • Uses CO2 method of extraction

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Lazarus Naturals
Lazarus Naturals
  • Vast range of flavors
  • Free shipping
  • High potency

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CBDistillery
CBDistillery
  • Moderately priced
  • Free shipping
  • Vast range of products

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cbd essence
CBD Essence
  • Twenty-four hours shipment
  • Focuses on small batches of production
  • Sprayer or dropper administration

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Royal-CBD-Oil
Royal CBD
  • Full spectrum
  • Multiple and high potencies
  • Variety of flavors

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Hemp Bombs Oil
Hemp Bombs
  • Multiple flavors
  • Multiple strengths
  • Third-party lab tested

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Best CBD Oil Brands 2023: Top 10 Rated & Buyer’s Guide

 CBDfx

CBDfx Oil

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This brand has a solid reputation for manufacturing high quality products. The brand offers a vast range of vegan-friendly and third-party-tested products.

  • High potency
  • Offers full-, broad spectrum, and CBD isolate options
  • Vegan friendly
  • Third-party tested
  • 30-day money-back guarantee
  • Few flavors

CBDfx has been in the industry for nearly a decade. The brand has mastered the art of producing top-notch quality products. CBDfx products contain various types of CBD oil and come in multiple potencies ranging from 500mg to 6000mg of CBD. The company is located in San Fernando Valley and has gradually become one of the largest CBD firms. CBDfx CBD Oil offers a full spectrum, broad spectrum, and CBD isolates; therefore, you can choose depending on your body’s tolerance levels and desired results. This CBD oil undergoes third-party laboratory testing from ISO-approved laboratories; therefore, you can be certain they are safe for human consumption. You can enjoy CBD tinctures, gummies, topicals, capsules, vapes, pet treats, and many more.

Users buy CBDfx CBD oils for pain management, improving sleep quality, relaxing, boosting pets’ health, and relieving anxiety-related symptoms. These products are manufactured in GMP-certified facilities and are all made from organic hemp. This is an excellent and highly effective option if you want to enjoy a vegan-friendly CBD oil.

Spruce CBD

Spruce CBD Oil

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This CBD oil is obtained from an heirloom hemp strain. Spruce CBD offers high-potency CBD oil that undergoes third-party lab testing and is free from artificial additives or sweeteners.

  • High potency
  • Third-party lab testing
  • No artificial sweeteners or additives
  • Made from organic hemp
  • Limited range of products
  • Relatively pricey

Spruce CBD is one of the newest CBD oil companies and has quickly gained a positive reputation. The brand prides itself on offering top-notch CBD oils that come in different products. You can enjoy Spruce CBD oil as cream, lotions, gummies, oils, and many more. These products contain full-spectrum CBD oil; therefore, you can enjoy the entourage effect from flavonoids, essential oils, terpenes, and other cannabinoids. These products are naturally flavored, with no artificial sweeteners or flavors. Spruce CBD oil is an excellent option if you prefer unflavored CBD products. It comes in high potency ranging from 750mg to 2400mg of CBD. Also, you do not have to worry about the brand’s purity; these products are subjected to thorough screening by third-party laboratories to guarantee potency, safety, and quality. These CBD products come with a 30-day money-back guarantee for all unopened containers.

Joy Organics

Joy Organics

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Joy Organics is an excellent option if you want to enjoy all the chemical compounds in a cannabis plant without THC. The brand offers USDA-approved broad-spectrum oil products.

  • THC free
  • Free shipping
  • USDA approved organic
  • Third-party lab tested
  • No international shipping
  • Expensive

This is an excellent choice if you are looking for top-notch quality broad-spectrum products. Joy Organics is dedicated to offering stellar quality and effective broad-spectrum oil.  The company offers relatively affordable products that offer a variety of health benefits, including reducing pain and anxiety and improving sleep quality. These products come in various flavors, such as orange Bliss, Fresh Lime, and Tranquil Mint. Besides, if you are looking for low-dosage broad-spectrum CBD oil, Joy Organics has covered that. These products come in moderate strength that ranges from 15mg to 75 mg of CBD per serving. Joy Organic CBD-infused products include CBD topicals, gummies, tinctures, salves, soft gels, and pet products. They all come with a 90-day money-back guarantee and free carbon-neutral shipping. If you are within any state within the USA, you can enjoy free shipping for these THC-free and broad-spectrum CBD oil products.

CBDPure

CBDPure Oil

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This is an excellent option if you are looking for an all-organic CBD oil. CBDPure offers top-tier quality CBD oils obtained from organic hemp.

  • All-organic
  • 90-day money-back guarantee
  • Full spectrum CBD
  • Multiple potencies
  • Third-party lab tested
  • Limited range of products
  • No flavor options

CBDPure offers premium quality products that contain all-natural hemp seed oil. The brand sources hemp from Washington and Colorado, where it is organically farmed and, therefore, free from additives, pesticides, or chemicals. You can enjoy a variety of products, including CBD edibles, topicals, capsules, tinctures, beverages, topical, Dab and Wax, and many more. These products undergo third-party tests to guarantee efficacy and safety. They come in multiple potencies that range from 300 mg to 1000mg of CBD per bottle. These CBD products contain full spectrum oil; therefore, you can enjoy all the chemical compounds from a cannabis plant and maximize the products’ potency. Also, the company offers a 90-day money-back guarantee for all products. If you are sensitive to any amount of THC, remember these products have traces of THC.

Nuleaf Naturals

NuLeaf Full Spectrum Hemp CBD Oil

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This CBD oil company provides CBD products that come in equal concentrations. Nuleaf is an excellent option for beginners since it removes the proper dosage hassle.

  • Third-party lab tested
  • Contains 60 mg of CBD
  • Uses CO2 method of extraction
  • Full spectrum CBD
  • Contains THC
  • Limited range of products

If you are new to the world of CBD, the dosage might be a hassle, therefore, overwhelming. All CBD oil tinctures from Nuleaf come with 60 mg of CBD per container. This consistency makes these CBD products provide prominent results for the customers. If you are looking to enjoy the entourage effect from all the chemical compounds from a cannabis plant, the brand’s CBD oil tinctures contain full spectrum oil. They contain CBC, CBG, CBN, and other cannabinoids in a hemp plant.

The company uses the best method of extraction, the C02 extraction method; therefore, you can be certain the CBD oil is of top-notch quality. You can enjoy various health benefits from the brand’s CBD gummies, oils, and capsules. The company is not stocked with a vast range of products; however, the ones available are just as effective. They are also third-party tested to guarantee efficacy, quality, purity, and safety. If you choose this brand but are new to CBD, please begin with a small dosage as you gradually monitor your body’s response. Also, if you are highly sensitive to THC, note that full-spectrum oil contains THC within the 0.3% legal limit.

Lazarus Naturals

Lazarus Naturals

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This company offers a vast range of products that come in multiple flavors. If you do not want to feel CBD’s earth taste, you can cruise around this brand’s vast range of flavored products.

  • Vast range of flavors
  • Free shipping
  • High potency
  • Contains organic coconut MCT oil
  • Some users dislike the taste

Lazarus Naturals is an excellent option for anyone looking to consume CBD oil in multiple tasty flavors. These products come in multiple flavors, including Apple cider, chai tea latte, mint chocolate, and many more. The brand offers CBD capsules, chocolate bars, topicals, gummies, coconut oil, and pet products. These products have a COA and undergo third-party lab testing from ISO 17205-approved laboratories. You can enjoy a variety of health benefits, such as pain and anxiety relief, from consuming these products.

The brand sources hemp from Oregon, one of the best places for obtaining organically grown hemp. Also, these products contain coconut MCT oil as the carrier oil despite having a vast range of flavors.  Products from Lazarus Naturals come in high and moderate potency that ranges from 20 mg to 50mg of CBD per ml. The company offers full-spectrum and broad-spectrum CBD oil; therefore, you can choose depending on the desired results and your body’s tolerance level.

 CBDistillery

CBDistillery

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If you are looking for CBD oil that is pocket-friendly, CBDistillery is an excellent option. The company offers a vast range of high quality CBD products that come in various flavors.

  • Moderately priced
  • Free shipping
  • Vast range of products
  • Limited range of flavors

This brand offers full-spectrum and broad-spectrum products that come in multiple potencies ranging from 500mg to 5000mg of CBD per container. These products are pocket friendly; however, this does not imply they are mediocre quality or less effective. The company uses organic hemp farms in the USA and is certified by the USA Hemp Authority. These Non-GMO products include CBD oil tinctures, capsules, topicals, powders, drink mixes, pet products, and gummies. By buying these CBD products, you can enjoy pain management, anxiety relief, anti-inflammatory benefits, and better sleep quality. Also, they all come with a 60-day money-back guarantee and various coupons and discount codes when you order from the company’s official website.

CBD Essence

cbd essence

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This brand is one of the most highly effective and reputable companies. Buying CBD oil from CBD Essence implies receiving fresh products made within 24 hours of delivery.

  • Twenty-four hours shipment
  • Focuses on small batches of production
  • Sprayer or dropper administration
  • 60-day money-back guarantee
  • Third-party tested
  • Ships to USA and Canada only

This is an excellent choice for anyone looking for a quick fix in small batches. The brand designs small batches of top-tier grade CBD-infused products that come with a 60-day money-back satisfaction. The company has been in the industry for nearly a decade now and has fully mastered what customers need. CBD Essence offers a vast range of products, including CBD edibles, tinctures, capsules, pet products, and many more. These products contain full-spectrum CBD that comes in multiple potencies that range from 300mg to 2400mg of CBD per ml. CBD Essence also offers a variety of flavors, including spearmint, cinnamon, mango, and grape.  The company’s products are administered sublingually, and all orders are made within one day of shipping. You can select a sprayer or dropper for your CBD oil.

Royal CBD

Royal-CBD-Oil

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This company uses organic hemp to make lab-tested products. These products contain full-spectrum oil and come in multiple potencies.

  • Full spectrum
  • Multiple and high potencies
  • Variety of flavors
  • Contains organic hemp
  • Easy to dose
  • Relatively expensive
  • Limited range of products

Royal CBD is a reputable firm that prides itself in offering stellar quality full spectrum products. These products are infused with CBD oil obtained through the CO2 extraction method, one of the safest and most effective CBD oil extraction methods. These products come in high and multiple potencies ranging from 250 mg to 2500mg of CBD per container. The brand makes dosing easier by offering a dropper designed to accurately and specifically measure one milliliter of CBD oil. These products come in various flavors, including natural mint, berry, and vanilla. The company’s products are safe and pure since they undergo third-party lab testing to guarantee purity, safety, potency, and quality. You can also enjoy free shipping for all orders when you buy from the brand’s official website.

Hemp Bombs

Hemp Bombs Oil

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You can get high quality CBD oil tincture from Hemp Bomb. These products contain full spectrum, broad spectrum, and pure CBD and come in multiple tasty flavors.

  • Multiple flavors
  • Multiple strengths
  • Third-party lab tested
  • Offers pure CBD
  • Offers saving and subscription services
  • Limited information about the company

The brand offers a full spectrum of pure CBD and broad-spectrum CBD oil. Hemp Bombs claims that it uses hand-selected and high quality raw CBD ingredients in all its products. You can buy a variety of products from this company, including CBD topicals, gummies, capsules, edibles, and pet products. These products contain pure CBD, full spectrum, and broad-spectrum CBD oil. You can choose the type of CBD that suits your needs and your body’s tolerance levels to CBD. They also come in multiple potencies that range from 300mg to 5000mg of CBD per container. These products are high quality and safe as they are third-party lab tested and accompanied by a COA. Also, the company offers a 30-day money-back guarantee for each CBD product.

What is CBD oil?

CBD oil has become one of the most popular natural remedies for various physical and mental health problems. The cannabis plant[4] is a primary source of cannabidiol oil. The plant contains various chemical ingredients; however, CBD oil is extracted since it has no psychoactive properties like THC (Tetrahydrocannabinol). CBD oil is then mixed with MCT oil or other carrier oils for dilution. CBD oil is used to relieve various health issues, such as pain and anxiety relief. Most CBD products are mostly preferred over prescription drugs because they have few mild side effects. You can find these products in online and offline stores, which come in gummies, creams, drinks, bath soaks, edibles, and many more.

CBD oil is legal in most states; however, forbidden in others. Also, they may be considered pharmacist-formulated CBD oils; however, they are not approved by the FDA. Therefore, always confirm the local rules and regulations regarding CBD-infused drugs when traveling.

Benefits Of CBD Oils

Relieving Pain

Relieving pain[5]: The use of CBD oil for pain relief and management dates back to centuries ago. Studies show that specific chemical compounds in a cannabis plant, for instance, CBD, can provide pain-alleviating benefits. The endocannabinoid[6] system is responsible for various vital functions in the human body, including immunity, pain sensation, sleep, and appetite.  The CBD oil reacts with the endocannabinoids[7] and can help in pain and inflammation reduction. Other reports[8] show that CBD, especially when combined with THC, can reduce pain in specific areas of the body, including the back and nerves. CBD oil can reduce pain[9] related to arthritis and sclerosis.

Boost Mental Health

Boost mental health[10]: Overall well-being includes being physically and mentally fit. Mental health issues such as depression, anxiety, and stress can interfere with an individual’s general health and wellness. These symptoms[11] are mostly treated using prescribed drugs; however, they might result in various side effects such as migraines, insomnia, sexual dysfunction, agitation, drowsiness, and many more. Others can even result in addiction or over-dependence on the said drug. On the other hand, CBD oil[12] is a more natural remedy to handle mental health problems. It can be used to alleviate symptoms related to anxiety, insomnia, PTSD[13], and depression[14].

Neuroprotective Properties

May reduce some symptoms related to cancer: Cancer[15]-related symptoms such as chronic pain, vomiting, and nausea can occur, especially from cancer treatment.  Suppose you have cancer and are seeking help from CBD oil; it is essential to consult your doctor first. These products might be effective for all cancer patients. Despite promising results, there is more study required to determine whether CBD oil should be applied more often in managing cancer-related symptoms.

Since CBD oil can stimulate the endocannabinoid system, it might also be beneficial for people suffering from neurological health disorders. Some studies[16] show that CBD can be helpful in treating MS, epilepsy, and other neurological disorders. It can also be used to reduce seizures for people suffering from Dravet syndrome[17]. More research is needed in these matters since some users have been associated with side effects such as fatigue, fever, and convulsions. However, Epidiolex is the only CBD product with FDA approval for treating seizures related to Dravet syndrome, Lennox-Gastaut, and epilepsy. This CBD product was approved in 2020 for treating seizures related to tuberous sclerosis complex[18].

Boost heart health

Hypertension[19] has been associated with deteriorating health and can result in metabolic syndrome, heart attack, and stroke. Studies show that CBD oil can be beneficial to the cardiovascular system. It can help in reducing blood pressure levels.  

Types of CBD

The method of CBD extraction determines what type of CBD oil can be obtained. CBD oil can be categorized into three, including full spectrum, broad spectrum, and CBD isolates oil. Full spectrum[20] oil contains all the chemical compounds of a cannabis plant. It also contains THC within the legal limit of 0.3%. Broad-spectrum[21] CBD oil contains all the chemical compounds in cannabis botanicals except THC; it has trace amounts of THC. Isolate CBD oil is pure CBD oil. This is the most pure form of CBD; unlike full spectrum and broad spectrum CBD oil, pure CBD oil does not contain any chemical compounds of cannabis; CBD isolate is pure.

How We Chose the Best CBD Oils

These brands use organic hemp extract to make some of the highly reputable and most effective CBD-infused products. We have ranked these CBD companies based on flavor options, dietary friendliness, potencies, and prices. Dietary friendliness implies that we evaluate the carrier oil’s quality applied and check whether the CBD product is gluten-free; or vegan-friendly. The following are among the various factors we consider when choosing premium CBD oil items:

  • Source of hemp
  • Third-party la testing results
  • Return Policies
  • Flavor options
  • Subscription and saving options
  • Customers reviews
  • Company’s reputation
  • Shipping time
  • Money-back guarantee
  • Customer service

How to Take CBD Oil?

There are various methods of consuming CBD, they include:

  • Orally: this includes taking CBD oil or capsules with your beverage or meal
  • Topically: This involves applying the CBD-infused product to your skin directl
  • Inhaling: this involves using vape cartridges to consume CBD
  • Transdermally: this involves placing CBD patches on the skin and letting it penetrate the bloodstream through the skin
  • Sublingually: this involves placing the CBD oil under the tongue and then swallowing it after at least sixty seconds

Always follow the manufacturer’s instructions when using these products.  This helps to prevent overdose and misuse and maximizes the product’s potency

Side Effects of CBD Oils

Epidiolex[22] is the only FDA-approved CBD-infused product. This product is formulated to treat Dravet syndrome and Lennox-Gastaut. Most people generally tolerate CBD oil; however, it can cause various side effects[23] such as vomiting, nausea, dry mouth, mood change, drowsiness, dizziness, diarrhea, and appetite changes.

CBD Oil Dosage

CBD pills, capsules, and gummies come with pre-measured CBD oil in each serving. However, CBD oil comes with a dropper and details the CBD amount in each drop. This leaves the user in a game of calculating how many drops are needed. This might be overwhelming, especially if you are new to these products. The most important factor in CBD oil dosage is following the manufacturer’s instructions to the latter. If you are unsure about the dosage, always consult customer care about the product.

Conclusion

Generally, CBD oil is associated with various health benefits. More research is required to verify these CBD-related health benefits completely. However, the results are quite promising. Stellar-quality CBD products are made from organic hemp plants and come with a certificate of Analysis guaranteeing that the products are free from molds, heavy metals, or pesticides. They also undergo third-party laboratory testing in ISO 17025-certified laboratories. Be aware when purchasing these products since some brands offer poor-quality products that might harm your health.

Frequently Asked Questions (FAQs)

Is CBD legal?

These products are legal in some states and illegal in others. Therefore, always check the state laws when traveling or attempting to access these products.

How much CBD is enough?

This depends on the desired results and your body’s CBD tolerance levels.s do not have psychoactive properties.

Does the FDA approve?

Epidiolex[24] is the only FDA-approved CBD-infused product. This product is formulated to treat Dravet syndrome and Lennox-Gastaut.

Are there side effects?

Some users report side effects[25] such as vomiting, nausea, dry mouth, mood change, drowsiness, dizziness, diarrhea, and appetite changes.

How can these benefits help my health?

These products are associated with various health benefits, including pain management, anxiety relief, seizure prevention, sleep quality, and many more.

What should I check before buying CBD-infused products?

There are various factors to consider, such as third-party lab testing, source of hemp, brand reputation, customer reviews, pricing, and many more.

Is there an age limit?

The allowed legal limit to consume CBD is between 18-21 years, depending on your state.

Is CBD safe?

Generally yes. However, if you have any underlying medical condition, please consult a healthcare provider before using these products.

+ 25 sources

MIDSS has strict procurement guidelines and relies on peer-reviewed studies, academic research institutes and medical associations. We work primarily with peer-reviewed studies to ensure accuracy. We avoid using tertiary references. For more information on how we ensure the accuracy and timeliness of our content, please see our editorial policy.

  1. VanDolah, H.J., Bauer, B.A. and Mauck, K.F. (2019). Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings, [online] 94(9), pp.1840–1851. doi:10.1016/j.mayocp.2019.01.003.
  2. Journal of Dietary Supplements. (2020). Differentiating Full-Spectrum Hemp Extracts from CBD Isolates: Implications for Policy, Safety and Science. [online] Available at: https://www.tandfonline.com/doi/abs/10.1080/19390211.2020.1776806?journalCode=ijds20 [Accessed 19 Oct. 2022].
  3. Corroon, J. and Phillips, J.A. (2018). A Cross-Sectional Study of Cannabidiol Users. Cannabis and Cannabinoid Research, [online] 3(1), pp.152–161. doi:10.1089/can.2018.0006.
  4. and, E., Health, Board and Evidence, A. (2017). Cannabis. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK425762/ [Accessed 19 Oct. 2022].
  5. Hill, K.P., Palastro, M.D., Johnson, B. and Ditre, J.W. (2017). Cannabis and Pain: A Clinical Review. Cannabis and Cannabinoid Research, [online] 2(1), pp.96–104. doi:10.1089/can.2017.0017.
  6. Kilaru, A. and Chapman, Kent D. (2020). The endocannabinoid system. Essays in Biochemistry, [online] 64(3), pp.485–499. doi:10.1042/ebc20190086.
  7. Darkovska-Serafimovska, M., Serafimovska, T., Arsova-Sarafinovska, Z., Stefanoski, S., Keskovski, Z. and Balkanov, T. (2018). Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases. Journal of Pain Research, [online] Volume 11, pp.837–842. doi:10.2147/jpr.s160556.
  8. Eskander, MD, MBA, J.P., Spall, BS, J., Spall, BA, A., Shah, MD, MBA, R.V. and Kaye, MD, PhD, A.D. (2020). Cannabidiol (CBD) as a treatment of acute and chronic back pain: A case series and literature review. Journal of Opioid Management, [online] 16(3), pp.215–218. doi:10.5055/jom.2020.0570.
  9. Schilling, J.M., Hughes, C.G., Wallace, M.S., Sexton, M., Backonja, M. and Moeller-Bertram, T. (2021). Cannabidiol as a Treatment for Chronic Pain: A Survey of Patients’ Perspectives and Attitudes. Journal of Pain Research, [online] Volume 14, pp.1241–1250. doi:10.2147/jpr.s278718.
  10. Linares, I.M., Zuardi, A.W., Pereira, L.C., Queiroz, R.H., Mechoulam, R., Guimarães, F.S. and Crippa, J.A. (2019). Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Brazilian Journal of Psychiatry, [online] 41(1), pp.9–14. doi:10.1590/1516-4446-2017-0015.
  11. Shannon, S. and Opila-Lehman, J. (2016). Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report. The Permanente Journal, [online] 20(4). doi:10.7812/tpp/16-005.
  12. Elms, L., Shannon, S., Hughes, S. and Lewis, N. (2019). Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series. The Journal of Alternative and Complementary Medicine, [online] 25(4), pp.392–397. doi:10.1089/acm.2018.0437.
  13. Kubala, J. (2022). 11 Herbs and Supplements to Help Reduce Symptoms of Depression. [online] Healthline. Available at: https://www.healthline.com/nutrition/herbs-supplements-for-depression [Accessed 19 Oct. 2022].
  14. Blake, A., Wan, B.A., Malek, L., DeAngelis, C., Diaz, P., Lao, N., Chow, E. and O’Hearn, S. (2017). A selective review of medical cannabis in cancer pain management. Annals of Palliative Medicine, [online] 6(S2), pp.S215–S222. doi:10.21037/apm.2017.08.05.
  15. Flachenecker, P., Henze, T. and Zettl, U.K. (2014). Nabiximols (THC/CBD Oromucosal Spray, Sativex®) in Clinical Practice – Results of a Multicenter, Non-Interventional Study (MOVE 2) in Patients with Multiple Sclerosis Spasticity. European Neurology, [online] 71(5-6), pp.271–279. doi:10.1159/000357427.
  16. Flachenecker, P., Henze, T. and Zettl, U.K. (2014). Nabiximols (THC/CBD Oromucosal Spray, Sativex®) in Clinical Practice – Results of a Multicenter, Non-Interventional Study (MOVE 2) in Patients with Multiple Sclerosis Spasticity. European Neurology, [online] 71(5-6), pp.271–279. doi:10.1159/000357427.
  17. Devinsky, O., Cross, J.H., Laux, L., Marsh, E., Miller, I., Nabbout, R., Scheffer, I.E., Thiele, E.A. and Wright, S. (2017). Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. New England Journal of Medicine, [online] 376(21), pp.2011–2020. doi:10.1056/nejmoa1611618.
  18. Office (2020). FDA Approves New Indication for Drug Containing an Active Ingredient Derived from Cannabis to Treat Seizures in Rare Genetic Disease. [online] U.S. Food and Drug Administration. Available at: https://www.fda.gov/news-events/press-announcements/fda-approves-new-indication-drug-containing-active-ingredient-derived-cannabis-treat-seizures-rare [Accessed 19 Oct. 2022].
  19. Arshad Muhammad Iqbal and Jamal, S.F. (2022). Essential Hypertension. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK539859/ [Accessed 19 Oct. 2022].
  20. Cather, J.C. and Cather, J.C. (2020). Cannabidiol primer for healthcare professionals. Baylor University Medical Center Proceedings, [online] 33(3), pp.376–379. doi:10.1080/08998280.2020.1775437.
  21. Cather, J.C. and Cather, J.C. (2020). Cannabidiol primer for healthcare professionals. Baylor University Medical Center Proceedings, [online] 33(3), pp.376–379. doi:10.1080/08998280.2020.1775437.
  22. Abu-Sawwa, R. and Stehling, C. (2020). Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers. The Journal of Pediatric Pharmacology and Therapeutics, [online] 25(1), pp.75–77. doi:10.5863/1551-6776-25.1.75.
  23. Cannabis and Cannabinoid Research. (2021). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies | Cannabis and Cannabinoid Research. [online] Available at: https://www.liebertpub.com/doi/10.1089/can.2016.0034 [Accessed 19 Oct. 2022].
  24. Abu-Sawwa, R. and Stehling, C. (2020). Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers. The Journal of Pediatric Pharmacology and Therapeutics, [online] 25(1), pp.75–77. doi:10.5863/1551-6776-25.1.75.
  25. Cannabis and Cannabinoid Research. (2021). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies | Cannabis and Cannabinoid Research. [online] Available at: https://www.liebertpub.com/doi/10.1089/can.2016.0034 [Accessed 19 Oct. 2022].

ABOUT THE AUTHOR

Clarke, M., MBAHM
MBA in Healthcare Management
She is a professional blog post, article, researcher, and health writer. She has mastered the art of content writing by practicing for years and constantly learning. She is always ready and well equipped to write. It is always a pleasure to bring her skills to use and play her part in helping others achieve their objectives. She has 6 years of experience conducting research in Fitness and health care. She is MBA qualified and has written health content for 8+ years.

ABOUT MEDICAL REVIEWER

Sutton, D., MD
Medical Writer & Editor
Drew is a retired ENT doctor who now lives in the Southeastern US. He was a member of the American Academy of Otolaryngology and a Fellow of the American College of Surgeons. He has a bachelor’s degree in Biology and Psychology and an MD degree. He completed his internship in General Surgery and Residency in Otolaryngology-Head and Neck Surgery and practiced for almost 30 years in all aspects of ENT, including a specialization in disorders of the ear and skull base. Drew is passionate about communicating his clinical experiences and making his knowledge more accessible to the general public by medical writing.